About Signature

Diagnostic Innovation

Medical professionals are faced with a challenging set of circumstances. They need tools that will allow them to determine the cause of mental retardation and birth defects so that medical problems can be anticipated and treated.

Conventional cytogenetic testing often provides incomplete information because of limited resolution. The turnaround time is generally 7-10 days, and living cells are required.

Signature Genomic Laboratories, LLC (Signature) has circumvented these cytogenetic testing problems with diagnostic innovations that utilize their proprietary SignatureChip® technology: The SignatureChipWG™, SignatureChipOS™, and Signature PrenatalChip™. Click here to learn more about Signature technology.

Guidance for the Future

Signature Genomic Laboratories specializes in microarray technology, and is the leading innovator in diagnostic microarray testing, providing the fastest, most thorough, and most objective chromosome analysis available. Health care providers should consider ordering microarray analysis for patients for whom they routinely order conventional karyotyping, subtelomeric FISH, and/or single-locus FISH. Signature’s proprietary arrays simultaneously assay the genome at selected loci (view disorders tested by the SignatureChipWG™ and SignatureChipOS™) with a higher resolution than that available from conventional cytogenetic testing, increasing the possibility of finding a structural chromosome abnormality, and giving medical geneticists, genetic counselors, and other medical professionals the data that they need to diagnose, clinically manage, and inform their patients.

For prenatal cases, the Signature PrenatalChip™, in conjunction with prenatal karyotype analysis, provides a more comprehensive analysis of fetal chromosomes (view PrenatalChip Loci List). Click here to access Frequently Asked Questions for Physicians and Patients.

Signature Genomic Laboratories actively participates in internal and collaborative research projects. Signature is devoted to sharing discoveries and educating the scientific and medical communities about the applications, benefits and limitations of comparative genomic hybridization microarray technology through scientific publications, presentations and provision of resources.

History and Co-Founders

Signature Genomic Laboratories, LLC was established as a partnership between Signature Genomic Services, Pathology Associates Medical Laboratories and Sacred Heart Medical Center.

Signature Genomic Laboratories is the exclusive provider of the SignatureChipWG™, SignatureChipOS™, Signature MarkerChip™, and Signature PrenatalChip™ testing technology. Signature’s global headquarters is located in Spokane, Washington where it operates a state-of-the-art array-based comparative genomic hybridization (array CGH) diagnostic laboratory. Signature’s mission is to provide outstanding cytogenetic services using the latest diagnostic technologies.

The scientific directors and co-founders are Lisa G. Shaffer, Ph.D. (bio) and Bassem A. Bejjani, M.D. (bio). Drs. Shaffer and Bejjani are experts in clinical genetics, molecular genetics and cytogenetics. Together they have over 25 years of experience in clinical diagnostics and fully understand the potential of new technologies for transforming genetic diagnosis.

Signature Genomic Laboratories are CAP accredited # 7185391, CLIA certified # 50D1020924 and licensed as an LLC in the state of Washington. SGL is also licensed as an Out-of-State Clinical Laboratory in Florida, Rhode Island and California.

Awards and Nominations

Employment Opportunities

Please visit our employment page for information regarding employment at Signature Genomic Laboratories, including current job openings.

Contact Us

Signature Genomic Laboratories’ hours of operation are Monday through Saturday 8:00 am to 5:00 pm PST. For sample shipments, please contact Signature by telephone or email prior to submitting patient samples so that the shipment can be tracked. Signature accepts samples on Saturdays.

Click here to request literature/pricing details

For questions, comments, or additional information, please call, write or e-mail us at:

Signature Genomic Laboratories, LLC

2820 N. Astor Street
Spokane, WA 99207

Tel: 509.474.6840
Fax: 509.474.6839

info@signaturegenomics.com

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