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CPT Codes

Signature Microarrays

Test Specimen Type CPT Codes
SignatureChipOS™ /

Signature PrenatalChip®OS		 Peripheral Blood 88386(x6), 83891
DNA 88386(x6)
Cultured Cells 88386(x6), 83891, 88241
Direct Amniotic Fluid 88386(x6), 83891, 88235
Tissue, Skin, or Products of Conception (POC) 88386(x6), 83891, 88233
Signature PrenatalChip®TE DNA 88386(x4)
Cultured Cells 88386(x4), 83891, 88241
Direct Amniotic Fluid 88386(x4), 83891, 88235
Tissue, Skin, or Products of Conception (POC) 88386(x4), 83891, 88233

SignatureFISH

Test Specimen Type CPT Codes
FISH (1 locus)
Peripheral Blood 88230, 88271(x2)*, 88283,
88273(x2)*, 88291
Tissue, Skin, Products of Conception (POC) 88233, 88271(x2)*, 88283,
88273(x2)*, 88291
Amniotic Fluid 88235, 88271(x2)*, 88283,
88273(x2)*, 88291
FISH (2 loci)
 Peripheral Blood 88230, 88271(x4)*, 88283(x2),
88273(x4)*, 88291(x2)
Tissue, Skin, Products of Conception (POC) 88233, 88271(x4)*, 88283(x2),
88273(x4)*, 88291(x2)
Amniotic Fluid 88235, 88271(x4)*, 88283(x2),
88273(x4)*, 88291(x2)

* Includes control FISH probe

Signature Karyotype

Test Specimen Type CPT Codes
G-Banded Karyotype
Peripheral Blood 88230(x2), 88262, 88291
Tissue, Skin, Products of Conception (POC) 88233(x2), 88262, 88291
Amniotic Fluid 88235(x2), 88262, 88291

Other

Test CPT Codes
MCC
 83900, 83901(x14), 83912, 83909, 83890
Fragile X
 83891, 83894(x2), 83892(x2), 83898, 83912, 83896, 83897
AFP
 82106
AChE
 82013

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Signature Genomic Laboratories was the first laboratory to provide microarray based cytogenetic diagnostics with its proprietary SignatureChip® and is the leader in providing microarray based chromosome analysis. Signature's worldwide client base includes clinical geneticists, neurologists, pediatricians, neonatologists, obstetricians, and the research community.