CPT Codes

Signature Precision Panel™ | Prenatal
Test Specimen Type CPT Codes
Signature
Precision Panel™ | Prenatal
Any 88271(x20), 83891, 88291*

* Please exclude this code if Signature Genomics is performing Karyotype in addition to Precision Panel™ | Prenatal.

Signature Microarrays
Test Specimen Type CPT Codes
SignatureChipOS® /

Signature PrenatalChip®OS
Peripheral Blood 88386(x6), 83891
DNA 88386(x6)
Cultured Cells 88386(x6), 83891, 88241
Direct Amniotic Fluid 88386(x6), 83891, 88235
Tissue, Skin, or Products of Conception (POC) 88386(x6), 83891, 88233
Signature
PrenatalChip®TE
DNA 88386(x4)
Cultured Cells 88386(x4), 83891, 88241
Direct Amniotic Fluid 88386(x4), 83891, 88235
Tissue, Skin, or Products of Conception (POC) 88386(x4), 83891, 88233
Signature FISH
Test Specimen Type CPT Codes
FISH (1 locus)
Peripheral Blood 88230, 88271(x2)*, 88283,
88273(x2)*, 88291
Tissue, Skin, Products of Conception (POC) 88233, 88271(x2)*, 88283,
88273(x2)*, 88291
Amniotic Fluid 88235, 88271(x2)*, 88283,
88273(x2)*, 88291
Chorionic Villus Sampling (CVS) — cultures or direct specimen 88235, 88271(x2)*, 88283,
88273(x2)*, 88291
FISH (2 loci)
Peripheral Blood 88230, 88271(x4)*, 88283(x2),
88273(x4)*, 88291
Tissue, Skin, Products of Conception (POC) 88233, 88271(x4)*, 88283(x2),
88273(x4)*, 88291
Amniotic Fluid — cultures or direct specimen 88235, 88271(x4)*, 88283(x2),
88273(x4)*, 88291
Chorionic Villus Sampling (CVS) — cultures or direct specimen 88235, 88271(x4)*, 88283(x2),
88273(x4)*, 88291
Signature Karyotype
Test Specimen Type CPT Codes
G-Banded Karyotype
Peripheral Blood 88230(x2), 88262, 88291
Tissue, Skin, Products of Conception (POC) 88233(x2), 88262, 88291
Chorionic Villus Sampling (CVS) — cultures or direct specimen 88235, 88269, 88280, 88291
Amniotic Fluid — cultures or direct specimen 88235, 88269, 88280, 88291
Other
Test CPT Codes
MCC
83900, 83901(x14), 83912, 83909, 83890
Fragile X
83891, 83894(x2), 83892(x2), 83898, 83912, 83896, 83897
AFP
82106
AChE
82013

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