OncoChip™ Testing Options
Signature Genomics recognizes the variability of each hematologic cancer case and offers a broad menu of testing services that can be ordered to suit the needs of each individual case.
- Signature Genomics offers a Copy Number Evaluation array for a whole genome assessment of copy number gains and losses associated with hematologic malignancy.
- In addition, Signature Genomics offers several disease specific panels for the detection of balanced translocations. Each of these translocation assessment arrays simultaneously tests for a group of balanced translocations that are seen in a specific cancer type.
- Each of the OncoChip™ panels can be ordered individually or in combination with one or more additional panels. They are intended to complement traditional karyotype but can be used stand alone.
- Some of the disease specific panels have two tiers available. The first tier panels are used to detect translocations that are more commonly seen. The second tier panels are used to detect translocations that are less frequent.
Signature Oncology Testing Menu
Each OncoChip™ test option can be ordered individually or in combination with others.
Choose the test option to suit the needs of each case.
Copy Number Evaluation
Translocation Assessment Panels for Specific Diseases
- Acute myeloid leukemia (AML)/Myelodysplastic syndromes (MDS)
- B-cell Acute lymphoblastic leukemia (ALL)
- Chronic lymphocytic leukemia (CLL)/Lymphoma
- Chronic myelogenous leukemia (CML)/Myeloproliferative neoplasms (MPN)
- T-cell Acute lymphoblastic leukemia (ALL)
- Multiple Myeloma
Translocation Assessment Panel for Multiple Diseases
Clinical Vignettes
- Progression of myelodysplastic syndrome
- Determining prognosis in acute lymphoblastic leukemia
- Determining prognosis in acute lymphoblastic leukemia when standard cytogenetic methods do not provide an answer
- Acute myeloid leukemia with normal karyotype
- Improving detection of aberrations in multiple myeloma