Signature Genomics' Oncology Testing
High resolution microarray analysis for the detection
of chromosome abnormalities associated with hematological malignancies including gains, losses and balanced translocations.
Signature Genomics uses the Signature OncoChip™ technology. OncoChip™ findings have the potential to clarify or alter diagnosis and prognosis and reclassify disease.
Key Service Features
- With the use of OncoChip™ technology, Signature can detect all clinically relevant copy-number imbalances commonly seen by chromosome analysis as well as submicroscopic gains and losses not visible by cytogenetics
- With the use of OncoChip™ technology, Signature can precisely and simultaneously identify balanced translocations as well as the translocation breakpoints and their partners not distinguishable by FISH and chromosome analysis
- Signature uses its proprietary Oncoglyphix™ software to provide our Directors with a rapid, whole genome data review for assistance in evaluation of results
- Results are available from Signature’s laboratory in 5–7 days which aids in resolving acute cases quickly
- The test panels run by Signature are selected by the customer from a broad menu of cancer specific options in order to suit the needs of each individual case
OncoChip™ Specifications
- Signature-designed 135K microarray
- More than 1,800 genes targeted with known or potential relevance to cancer
- Detects copy number abnormalities down to 10 kb in targeted regions and 140 kb in the genomic backbone
Exemplary Service and Support
- ABMG Certified Cytogenetic Directors issue reports and interpretation
- Directors and/or Laboratory-based Genetic Counselors are available for consultation, before, during, and after the testing process
- Exceptional, easy-to-read reports are focused on reporting clinical relevance
- CLIA certified, CAP accredited, ISO 9001 certified
OncoChip™ Testing Options
Signature Genomics recognizes the variability of each hematologic cancer case
and offers a broad menu of testing services that can be ordered to suit the needs of each individual case.
To learn more about each of Signature Genomics Oncology testing services,
please visit the OncoChip™ Testing Options page.