Parental Testing Policies
Signature Genomic Laboratories recommends testing of parental samples in cases in which the patient is found to have an abnormal test result. Analysis of parental samples determines whether an abnormality is familial or de novo, and can provide clarification of interpretation and clinical relevance of the patient’s results.
Signature Genomics does not charge for parental analysis in cases in which parental samples are needed to interpret the array finding of unclear clinical relevance in the child or fetus. Signature Genomics charges a reduced price for parental analysis in cases in which parental testing is medically indicated (for example, a parent with similar clinical features to the child found to have a microdeletion or microduplication known or suspected to have clinical relevance) or testing is recommended as standard of care for estimation of recurrence risks and genetic counseling (for example, parental testing for a balanced chromosomal rearrangement.