Signature Precision Panel™ | Prenatal
The Signature Precision Panel™ | Prenatal tests for 20 common and severe microdeletion/duplication syndromes and common aneuploidies of chromosomes 13, 18, 21, X and Y within 24-48 hours.
Quick jump to: Signature Precision Panel™ | Prenatal: A Streamlined Timeline
The Signature Precision Panel™ | Prenatal can be combined with traditional karyotyping for a single diagnostic package that includes:
Rapid, targeted testing within 24–48 hours for:
-
The most common aneuploidies of chromosomes
13,18, 21, X, and Y1 - Up to 1 in 300 births have an aneuploidy of one of these 52
- 20 common and severe microdeletion/duplication syndromes
not usually detected by traditional karyotyping2–6 - Up to 1 in 1,126 births have one of these syndromes2–6
- Often missed by routine tests—anomalies may not appear on detailed sonography7,8
- Majority occur de novo (for the first time in an individual)
and therefore will not show up in family history3 - View the Disorders Tested / Incidence Rates table »
1 in 237
births affected by conditions covered by Precision Panel™2
TRADITIONAL KAROTYPING
- Standard chromosome analysis (plus AFP* and AChE† testing on amniotic fluid)
- Results in 10–14 days
CONFIRMATION OF ALL ABNORMAL RESULTS BY AN INDEPENDENT CYTOGENETIC TECHNOLOGY. GENETIC COUNSELOR SUPPORT AVAILABLE TO HEALTH CARE PROVIDERS FOR ALL RESULTS.
1 in 138
births have an abnormality detectable by the Signature Precision Panel™ | Prenatal diagnostic package2, ‡
* Alpha-Fetoprotein.
† Acetylcholinesterase.
‡ A negative test does not completely eliminate the possibility of a chromosome abnormality in the pregnancy.
The Signature Precision Panel™ | Prenatal: A Streamlined Timeline
* We recommend that maternal cell contamination (MCC) studies on female fetuses be performed in conjunction with this assay. Requires 3 to 5ml maternal blood in EDTA (purple-top tube). MCC studies will be charged separately.