Sample Requirements and Turn-Around Times,
Oncology Testing

Signature OncoChip™
Sample Type Quantity Required Turn-Around Times*
Extracted DNA 3µg DNA 5–7 days
Peripheral Blood (submit only if marrow unobtainable) 1 x EDTA vacutainer containing
5cc whole blood
5–7 days
Bone Marrow 1 x EDTA vacutainer containing 1–3cc 5–7 days
Lymph Node 3mm x 3mm biopsy in sterile media
or saline
5–7 days
Signature OncoFISH

OncoFISH is used only for the confirmation or monitoring of abnormalities after Signature OncoChip™

Sample Type Quantity Required Turn-Around Times*
Fixed Cell Pellet In Carnoy's fixative 7–10 days
Unstained Slides One slide per FISH probe set requested 7–10 days

General Specimen Handling Instructions

  • Please follow the procedure and use kit-included reagents for the stabilization of peripheral blood or bone marrow samples for use on the Signature OncoChip™.
  • Label all tubes/flasks with patient name and date of birth, and enclose completed paperwork. Include previous cytogenetic reports.
  • Samples should be shipped at room temperature in a rigid, leak-proof container by overnight delivery. Delayed shipment of sample or inappropriate temperatures may result in longer processing time or sample failure. Please notify Laboratory of courier tracking number.
  • Microarray turn-around times are usually 7 days for sufficient samples. If culturing is needed, or other services are requested, turn-around times may be longer. Samples received prior to 12:00pm (PT) are processed the same day, whereas samples received in the afternoon are processed the next working day.
  • For paraffin- or formalin-embedded tissue, please contact Signature Genomics.
  • Please contact laboratory at 509-474-6840 for further clarification or other questions.

* Turn-around times are approximate and based on receipt of adequate sample. Other services at Signature Genomics, such as cell culturing, culture expansion, karyotyping, or FISH confirmation, may increase turn-around times.

† Additional CPT codes may be billed if the sample received does not meet Signature Genomics specimen requirements.


1.877.Sig.Chip (744.2447) or 509.474.6840  •  info@signaturegenomics.com

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